Pediatric Severe Sepsis: Current Trends and Outcomes
PSS prevalence in PICUs has increased over the past decade, with an increased prevalence of comorbidities but a decrease in mortality. Individual center PSS prevalence, volume, and costs demonstrate variability and are significantly correlated with mortality. Further evaluation to identify clinical contributors to center-specific variability could identify opportunities for earlier sepsis identification and optimization of therapies.
Conclusions
PSS prevalence in PICUs has increased over the past decade, with an increased prevalence of comorbidities but a decrease in mortality. Individual center PSS prevalence, volume, and costs demonstrate variability and are significantly correlated with mortality. Further evaluation to identify clinical contributors to center-specific variability could identify opportunities for earlier sepsis identification and optimization of therapies.
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