Exercise Capacity, HRQoL in Asbestos Related Pleural Disease
This is the first investigation of the effect of ARPD on functional exercise capacity, demonstrating that this population has reduced functional exercise capacity measured by the 6MWT. This study has also established that people with ARPD have reduced HRQoL. Furthermore, we have shown the 6MWD correlated with peak exercise capacity, HRQoL and physical activity. The 6MWT would be a simple test to perform and integrate into clinical practice to determine functional exercise capacity in people with ARPD and may be a useful surrogate measure of peak exercise capacity and physical activity in the absence of cardiopulmonary exercise testing and activity monitors. With few treatment options available for people with ARPD, research is required to address whether the impairments of reduced exercise capacity and HRQoL are amenable to pulmonary rehabilitation.
Conclusions
This is the first investigation of the effect of ARPD on functional exercise capacity, demonstrating that this population has reduced functional exercise capacity measured by the 6MWT. This study has also established that people with ARPD have reduced HRQoL. Furthermore, we have shown the 6MWD correlated with peak exercise capacity, HRQoL and physical activity. The 6MWT would be a simple test to perform and integrate into clinical practice to determine functional exercise capacity in people with ARPD and may be a useful surrogate measure of peak exercise capacity and physical activity in the absence of cardiopulmonary exercise testing and activity monitors. With few treatment options available for people with ARPD, research is required to address whether the impairments of reduced exercise capacity and HRQoL are amenable to pulmonary rehabilitation.
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