Simple Pulmonary Eosinophilia
Important
It is possible that the main title of the report Simple Pulmonary Eosinophilia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Summary
Simple pulmonary eosinophilia (SPE), also known as Loeffler syndrome, is a rare, temporary (transient) respiratory disorder characterized by the accumulation of eosinophils in the lungs (pulmonary eosinophilia). Eosinophils are a type of white blood cell and are part of the immune system. They are usually produced in response to allergens, inflammation or infection and are particularly active in the respiratory tract. Most cases of SPE are believed to be due to an allergic reaction to drugs and infection (especially parasitic ones). SPE usually ranges in severity from individuals who do not develop any symptoms (outside of eosinophilia) to individuals who develop mild symptoms. In extremely rare cases, more significant complications can occur. Generally, no specific therapy is required as symptoms usually go away spontaneously without treatment.
Introduction
Simple pulmonary eosinophilia was first described in the medical literature in 1932. It is classified as a form of eosinophilic lung disease, a large group of interstitial lung diseases. SPE is considered a benign, self-limiting disorder.
Centers for Disease Control and Prevention
1600 Clifton Road NE
Atlanta, GA 30333
Tel: (404)639-3534
Tel: (800)232-4636
TDD: (888)232-6348
Email: cdcinfo@cdc.gov
Internet: http://www.cdc.gov/
NIH/National Heart, Lung and Blood Institute
P.O. Box 30105
Bethesda, MD 20892-0105
Tel: (301)592-8573
Fax: (301)251-1223
Email: nhlbiinfo@rover.nhlbi.nih.gov
Internet: http://www.nhlbi.nih.gov/
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Internet: http://rarediseases.info.nih.gov/GARD/
Campaign Urging Research for Eosinophilic Disease (CURED)
PO Box 32
Lincolnshire, IL 60069
Tel: (847)361-3292
Email: ellyn@curedfoundation.org
Internet: http://www.curedfoundation.org
Cincinnati Center for Eosinophilic Disorders
Cincinnati Children's Hospital Medical Center
3333 Burnet Avenue
MLC 2010
Cincinnati, OH 45229-3039
Tel: (513)636-2233
Fax: (513)636-9069
Tel: (800)344-2462
TDD: (513)636-4900
Email: cced@cchmc.org
Internet: http://www.cincinnatichildrens.org/eosinophils
American Partnership for Eosinophilic Disorders
PO Box 29545
Atlanta, GA 30359
Tel: (713)493-7749
Fax: (713)493-7749
Internet: http://www.apfed.org
It is possible that the main title of the report Simple Pulmonary Eosinophilia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
- Loeffler syndrome
- Löffler syndrome
Disorder Subdivisions
- None
General Discussion
Summary
Simple pulmonary eosinophilia (SPE), also known as Loeffler syndrome, is a rare, temporary (transient) respiratory disorder characterized by the accumulation of eosinophils in the lungs (pulmonary eosinophilia). Eosinophils are a type of white blood cell and are part of the immune system. They are usually produced in response to allergens, inflammation or infection and are particularly active in the respiratory tract. Most cases of SPE are believed to be due to an allergic reaction to drugs and infection (especially parasitic ones). SPE usually ranges in severity from individuals who do not develop any symptoms (outside of eosinophilia) to individuals who develop mild symptoms. In extremely rare cases, more significant complications can occur. Generally, no specific therapy is required as symptoms usually go away spontaneously without treatment.
Introduction
Simple pulmonary eosinophilia was first described in the medical literature in 1932. It is classified as a form of eosinophilic lung disease, a large group of interstitial lung diseases. SPE is considered a benign, self-limiting disorder.
Resources
Centers for Disease Control and Prevention
1600 Clifton Road NE
Atlanta, GA 30333
Tel: (404)639-3534
Tel: (800)232-4636
TDD: (888)232-6348
Email: cdcinfo@cdc.gov
Internet: http://www.cdc.gov/
NIH/National Heart, Lung and Blood Institute
P.O. Box 30105
Bethesda, MD 20892-0105
Tel: (301)592-8573
Fax: (301)251-1223
Email: nhlbiinfo@rover.nhlbi.nih.gov
Internet: http://www.nhlbi.nih.gov/
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Internet: http://rarediseases.info.nih.gov/GARD/
Campaign Urging Research for Eosinophilic Disease (CURED)
PO Box 32
Lincolnshire, IL 60069
Tel: (847)361-3292
Email: ellyn@curedfoundation.org
Internet: http://www.curedfoundation.org
Cincinnati Center for Eosinophilic Disorders
Cincinnati Children's Hospital Medical Center
3333 Burnet Avenue
MLC 2010
Cincinnati, OH 45229-3039
Tel: (513)636-2233
Fax: (513)636-9069
Tel: (800)344-2462
TDD: (513)636-4900
Email: cced@cchmc.org
Internet: http://www.cincinnatichildrens.org/eosinophils
American Partnership for Eosinophilic Disorders
PO Box 29545
Atlanta, GA 30359
Tel: (713)493-7749
Fax: (713)493-7749
Internet: http://www.apfed.org
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