What is Naproxen?

• Naproxen is an over-the-counter nonsteroidal anti-inflammatory drug. NSAIDs are pain and inflammation relievers. According to Drugs.com, naproxen works by reducing hormones in the body that trigger pain and swelling. It is used to treat arthritis, spondylitis, menstrual cramps, fever, inflammation and general pain.
  
  

Uses in Dogs

• Naproxen can be used to treat arthritis, joint pain and muscle pain in dogs. It should not be a long-term solution for pain; the Merck Veterinary Manual reports that dogs receiving naproxen for three to seven days can experience symptoms of toxicity. Always consult your veterinarian before administering any medication to you dog, and never give naproxen to cats.
  
  

Dosage

• According to VetInfo.com, the published dosage for dogs is 1.1 to 2.2 mg of naproxen per kilogram of weight (divide weight in pounds by 2.2 to calculate kilograms). Give this dose once per day or once every other day. Keep in mind that naproxen is not eliminated from the dog's system for 34 to 72 hours, according to the Merck Vet Manual.
  
  

Toxicity

• If your dog receives too high a dose of naproxen or is given naproxen for too many days, there is a risk of overdose, internal bleeding and ulcers. The U.S. National Library of Medicine explains that naproxen can potentially impair prostaglandin production, which leads to a decrease in gastrointestinal mucus. This, in combination with the acidity of naproxen, may result in ulcers and internal bleeding.
  
  

Symptoms of Toxicity

• Symptoms of naproxen overdose include vomiting, melena, abdominal pain, salivation, general weakness and bloody stool or vomit, according to theU.S. National Library of Medicine. If your dog exhibits any of these symptoms and has been taking naproxen or any other NSAID, see your veterinarian immediately as toxicity can result in serious injury and death.