The Cast of Dirty Sexy Money: Peter Krause as Nick George, Donald Sutherland as Tripp Darling, William Baldwin as Patrick Darling, Natalie Zea as Karen Darling, Glenn Fitzgerald as Rev. Brian Darling, Samaire Armstrong as Juliet Darling, Seth Gabel as Jeremy Darling, Zoe McLellan as Lisa George and Jill Clayburgh as Letitia Darling.