Dr. Maurie Markman comments on a study in Journal of Clinical Oncology demonstrating the increased risk for visceral spread of ovarian cancer with BRCA1/2 mutations....More...

This article reviews the state of the art in next-generation genome sequencing platforms, which offer massive increases in both time and cost-effectiveness over older methods....More...

Dr. Ari VanderWalde summarizes key sessions from AACR 2010 discussing how cancer genomic and biomarker research is translating to the clinic....More...

This review summarizes recent progress in isolating biomarkers which might predict which patients will have the greatest benefit from antidepressant therapy for depression and other mood disorders....More...

How can pharmacogenomics be applied to post-transplant immunosuppressive therapy? This review explores how genetic profiles may inform drug selection, improving efficacy and limiting toxicity....More...

Dr. Maurie Markman discusses the clinical value of identifying an uncommon KRAS mutation in patients with BRCA-negative ovarian cancer and a strong family history of the disease....More...

Drs. Gil Melmed and Dermot McGovern comment on a recent study in Nature Genetics identifying new SNPs associated with susceptibility to celiac disease....More...

This review investigates the contributions of genomic factors in explaining sub-optimal response to currently used antiemetics for combating the nausea and vomiting of chemotherapy....More...

Dr. Ali Torkamani reviews a recent paper suggesting a genetic link between type 2 diabetes and risk for colorectal cancer -- or possibly vice versa....More...