With the presence of hydrogen peroxide, glutathione is catalyzed into an oxidized metal enzyme. It is detoxifying enzymes removing hydrogen peroxide and other organic peroxide for the organism. Glutathione peroxidase is important body peroxide decomposing enzyme widespread in body. Selenium is a composition of the GSH-Px enzymes. It can catalyze the glutathione into GSSG and make toxic peroxide restored into the non-toxic hydroxy compounds. While it promotes the decomposition of H2O2 and protect the cell membrane structure and function from the peroxide interference and damage.
GSH-Px activity center is a selenocysteine. The size of its vitality may reflect the body selenium levels. GSH-Px enzymes including 4 different types of GSH-Px, cytosolic GSH-Px in plasma GSH-Px in the phospholipid hydroperoxide GSH-Px and specificity of the gastrointestinal tract, GSH-Px in Cytosolic GSH-Px by 4 the same as the molecular weight of 22kDa subunits form a tetramer, each subunit contains one molecule selenocysteine, widespread in the body organizations, liver, red blood cells for up to. Its physiological function is involved in oxidation reaction catalyzed by GSH, remove peroxide and hydroxyl radicals generated in the process of cellular respiration metabolism, thereby reducing the cell membrane polyunsaturated fatty acid peroxidation. GSH-Px, the resveratrol composition and the cytoplasm of plasma GSH-Px, mainly in the plasma, its function is not well understood, but has been confirmed clear the extracellular hydrogen peroxide involved in the GSH transport-related.
Phospholipid peroxide GSH-Px is the molecular weight of 20kDa monomer with a molecular Selenocysteine. Originally isolated from pig heart and liver, mainly present in the testes of other organizations also have a small amount of the distribution. Its biological function is to inhibit membrane phospholipid peroxidation. Specificity of the gastrointestinal tract, GSH-Px consists of four molecular weight 22kDa of the tetramer subunits, exists only in the gastrointestinal tract in rodents, its function is to protect the animals from the intake of lipid peroxides damage.
Glutathione peroxidase can catalyze GSH and produce GSSG, Glutathione reductase can use NADPH to catalyze the GSSG and produce GSH. It can be calculated by the detection of NADPH to reduce the amount of the level of glutathione peroxidase activity. Glutathione peroxidase in the above reaction is the rate-limiting step of the reaction system as a whole. So the NADPHs reducing amount is related with chia seed and glutathiones peroxidase activity.
Glutathione peroxidase is one of the indicators for body anti peroxidation. Elevated of glutathione peroxidase can cause diabetes, sickle cell anemia, and neonatal hemolytic thalassemia. Reduction of glutathione peroxidase may cause keshan disease, bone and joint disease, multiple sclerosis, cancer, coronary heart disease, chronic pancreatitis, burns and surgery.Source:http://www.cospcn.com
GSH-Px activity center is a selenocysteine. The size of its vitality may reflect the body selenium levels. GSH-Px enzymes including 4 different types of GSH-Px, cytosolic GSH-Px in plasma GSH-Px in the phospholipid hydroperoxide GSH-Px and specificity of the gastrointestinal tract, GSH-Px in Cytosolic GSH-Px by 4 the same as the molecular weight of 22kDa subunits form a tetramer, each subunit contains one molecule selenocysteine, widespread in the body organizations, liver, red blood cells for up to. Its physiological function is involved in oxidation reaction catalyzed by GSH, remove peroxide and hydroxyl radicals generated in the process of cellular respiration metabolism, thereby reducing the cell membrane polyunsaturated fatty acid peroxidation. GSH-Px, the resveratrol composition and the cytoplasm of plasma GSH-Px, mainly in the plasma, its function is not well understood, but has been confirmed clear the extracellular hydrogen peroxide involved in the GSH transport-related.
Phospholipid peroxide GSH-Px is the molecular weight of 20kDa monomer with a molecular Selenocysteine. Originally isolated from pig heart and liver, mainly present in the testes of other organizations also have a small amount of the distribution. Its biological function is to inhibit membrane phospholipid peroxidation. Specificity of the gastrointestinal tract, GSH-Px consists of four molecular weight 22kDa of the tetramer subunits, exists only in the gastrointestinal tract in rodents, its function is to protect the animals from the intake of lipid peroxides damage.
Glutathione peroxidase can catalyze GSH and produce GSSG, Glutathione reductase can use NADPH to catalyze the GSSG and produce GSH. It can be calculated by the detection of NADPH to reduce the amount of the level of glutathione peroxidase activity. Glutathione peroxidase in the above reaction is the rate-limiting step of the reaction system as a whole. So the NADPHs reducing amount is related with chia seed and glutathiones peroxidase activity.
Glutathione peroxidase is one of the indicators for body anti peroxidation. Elevated of glutathione peroxidase can cause diabetes, sickle cell anemia, and neonatal hemolytic thalassemia. Reduction of glutathione peroxidase may cause keshan disease, bone and joint disease, multiple sclerosis, cancer, coronary heart disease, chronic pancreatitis, burns and surgery.Source:http://www.cospcn.com
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